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1、IOVIAWhitePaperOpportunitiesinMovingCareNearerthePatientiiYourorderhasbeendispatched/AARONWRIGHT,Ana1yst,Thought1eadership,IQVIATab1eofcontentsIntroduction1Aninterwoventapestry:E1ementsofnear-to-patientcare2Pointsofadministration2Te1ehea1thso1utions3Formu1ationsanddevices4Hurd1esontherunningtrack:Ch
2、a11engestoimp1ementation5Regu1atory5Financia15Behavioura161ogistica16Abountifu1harvest:Opportunitiesavai1ab1etostakeho1ders7Patients7Hea1thcaresystems8Pharmacompanies8Distributors9Pharmacies9Conc1usion10References11Abouttheauthors12Acknow1edgments12IntroductionThehea1thcaresectorhasincreasing1ymoved
3、towardstreatingpatientsatanindividua11eve1,bothintermsofpatientcentricityandpersona1isedmedicine.Aspartofthisphenomenonthereisagrowingfocusonprovidingpatientswithgreaterf1exibi1itywithwhereandwhentheyreceivecare.Itisimportanttostressthatthismovementisnotmere1y1ookingtoincreaseat-homede1iveryofmedici
4、nes,butinsteadtointroducestructura1changestohea1thcaresystems,focusingontreatingpatientsoutsideofthehospita1wherefeasib1e.Historica11ywehavea1readyseensuccessfu1caseswherecarehasbeenmovedoutofthehospita1,suchaswiththeadventofat-homedia1ysisortheGermanpracticeofspecia1istsresidinginoffices,ratherthan
5、hospita1s.Thetrendtowards*,near-to-patient,careispartofthebroadermovementwithinthehea1thcareandpharmaceutica1industriesovertheyearstofocusonmanagingapatient,scareonamoreindividua11eve1.Ithasa1sobeenacce1eratedinsomecasesbytheCOVID-19pandemic,suchaswasseenwiththegreaterdep1oymentofte1ehea1thso1utions
6、.Aninterwoventapestry:E1ementsofnear-to-patientcare,一.一一一ZFigure1:Carede1iverymethods帏!ftSMob1ec1inicHospita1Specia1tyc1inicGPsurgeryrf一rv1O:HomeHomewithHCPSe1f-adminSource:IQVIAEMEAThought1eadership.1oca1ityofcareNear-to-patientcareiscomprisedofamyriadoffactors,andthereisnoone-size-fits-a11approach
7、.Thefo11owingsectionwi11exp1orethreeimportantareas,name1ypointsOfadministration,te1ehea1thso1utionsandformu1ationsanddevices.POINTSOFADMINISTRATIONOneaspectiswhereandwhencareitse1fisadministered,inc1udingbutnot1imitedto: Outpatientc1inics,whichcanprovidecomp1extreatmentbutmayrequirepatientstotrave1s
8、omedistance(a1thoughsti11shorterthantrave1ingtoare1ative1yfewernumberofhospita1s). Mobi1ec1inics,whichcantrave1toremotepatientsandsti11providecomp1extreatments1ikeanoutpatientcentre,butatasma11erthroughputduetotheirsma11ercapacity. 1oca1pharmacies,whicharemorenumerousandmore1oca1thanoutpatientc1inic
9、s,butsti11requirepatientstotrave1andareun1ike1ytobeab1etoadministertreatmentsmorecomp1exthanIVformu1ations. At-hometreatment,withorwithoutanassistingHCP.At-hometreatmentcanbethemostconvenientoptionforpatientsbutrequiressignificantinvestmentin1ogisticsandpersonne1.Theseoptions,high1ightedinFigure1,ar
10、enotmutua11yexc1usive,andanear-to-patientcaresystemcancomprisemu1tip1ecareadministrationendpoints.Germanya1readyhasanear-to-patientsysteminp1acewiththeAmbu1anteSpezia1facharzt1icheVersorgung(ASV)systemwhicha11owsfortreatmentofcomp1exconditionsinc1inicsandpracticeswithouthospita1admission.Additiona11
11、y,intheUKsomepharmacieshavebeentransformedintouhea1thcarecentres,whichcanadministermedicationsaswe11astestingandscreening.)Near-to-patientcareissuitab1eforbothprimaryandsecondarycareandacrosshigh-va1uetherapyareas.Thetop3therapyareasbyva1uein2023inEurope(onco1ogy,immuno1ogyandantithrombotics)area11c
12、ompatib1ewithanear-to-patientcaresystem.Sotooareorphanmedicinesforrarediseases;tonamejustoneexamp1e,Onpattro(patisiran),amedicationforhATTRamy1oidosis,isavai1ab1eforhomeadministrationinIta1ythroughA1ny1amIta1iasAMYCAREprogramme.2Additiona11y,OnpattroisansiRNAtherapy,demonstratingthatnear-to-patientc
13、arecana1soworkwithadvancedtherapies.TE1EHEA1THSO1UTIONSThede1iveryofmedicinestopatientshomes,eitherusingprivatecouriersornationa1mai1carriers,grantsgreaterconveniencetopatientswhono1ongerneedtotrave1tohospita1sorpharmaciestopickuptheirmedications.Te1ehea1tha1socomprisesdigita1hea1thso1utions,inc1udi
14、ngte1econsu1tationsandte1ediagnosis,whichreducethenumberofin-personvisitsrequiredforbothpatientsandHCPs.Integratingc1inica1expertise,dataana1yticsanddigita1so1utionscanhe1phea1thcaresystemsachievekeyde1iverytargetsandhe1pimprovepopu1ationhea1th.Therearemanyothercomponentswithindigita1hea1ththatareap
15、p1icab1etoanear-to-patientcaresystemaswe11.Figure2:Month1ynumberofDiGAprescriptionsinGermanySource:IQVIADiseaseAna1yzerPane1,February2023.suowdudDQEa6UB5%Mobi1ephonesandInternetofThingsdevices1ikesmartwatchesa1sop1ayaro1e.Duetotheirincreasedcomp1exityandinc1usionofmanykindsofsensorsinc1udingcameras,gyroscopesandmicrophones,thesedevicescanco11ectvastamountsofhea1thdataforusersintheformofdigita1biomarkers.3ThisdatacaninturnbeusedbyHCPstoaidwithmonitoringofchronichea1thconditions,diagnosisandpreventativecareregimes,whi1stminimisingthenumberofin-personvisitsrequired.Digita1therapeutics(DTx),wh
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