专业课-《药理学》课程教学大纲(英文班).docx

《专业课-《药理学》课程教学大纲(英文班).docx》由会员分享，可在线阅读，更多相关《专业课-《药理学》课程教学大纲(英文班).docx（15页珍藏版）》请在第一文库网上搜索。

1、Sy11abusofPharmaco1ogy适用对象：供药学专业本科学生使用(学分：3c1asses：54)1. IntroductionPharmaco1ogyisanessentia1coursethatcontributesbasictheory,e1ementaryknow1edgeandscientificprincip1estodiseasespreventionandrationa1useofdrug.Itisa1soadoub1ebridgethat1inksmedicineandpharmacy,basicmedicineandc1inica1medicine.I1SChed

2、I11eandCOntent(含每章教学目的、基本教学内容和教学要求)：Chapter 1 druginventionandthepharmaceutica1industry1. PurposeUnderstandthepharmaco1ogydiscip1ines,thedeve1opmenthistoryofpharmaco1ogy.Understandthepharmaco1ogystudyobject,studymethodandmissioninmedicineandmedica1researchstatus,graspthebasicru1esofthepharmaco1ogica

3、1effects.2. Teachingcontent：(1) overviewofpharmaco1ogy(2) Thecontentofbasicpharmaco1ogy(3) researchmethodsinpharmaco1ogy(4) drugdiscoveryandc1inica1drugeva1uation(5) prec1inica1eva1uationChapter 2 pharmacokinetics1purpose：Graspthere1ationbetweenTransmembranetransporterandprocessofdruginthebody.grasp

4、theconceptionofBioavai1abi1ity,compartment,apparentvo1umeofdistribution,pharmacodynamics,p1asmadrugconcentrationandHa1f-1ife2. Teachingcontent：(1) Transmembranetransport(2) Processofdruginthebody(3) P1asmadrugconcentrationandHa1f-1ife(4) First-orderrateprocess,ero-orderrateprocessChapter 3 pharmacod

5、ynamics1 .PurposeUnderstandthebasicfunction,drugdependent,structureactivityre1ationship,drugtreatmentprincip1eandscope,safetyandindexpoisoneffect.2. Teachingcontent：(1) Thebasicfunctionofdrugs(2) Thebasicru1esofthedrugchapter8neurotransmissiontheautonomicandsomaticmotorNS1. Purpose:Graspthec1assific

6、ationoftheautonomicdrugspharmaco1ogy;themaintransmittersandreceptorsc1assification,type,distribution;autonomictransmitters,synthesis,transport,reserve,re1easeandmetabo1ism.2. Content：(1) C1assifyautonomicnervebytransmitter.(2) C1assifyautonomicnervesystembytransmitterreceptor.(3) TheGenera1actionpri

7、ncip1eofautonomicnervesystemdrugsChapter9muscarinicreceptoragonistsandantagonistsCho1inomimeticdrugs1. Purpose:Grasptheconceptionandc1assificationofthecho1inereceptoragonists;understandtheN-IikeandM-Iikefunctionofacety1cho1ine.Graspthepharmaco1ogica1action,c1inica1app1icationandadversereactionofcarp

8、i1ineandneostigmine.2. Content：(1) Conceptionandc1assificationofthecho1inereceptoragonists.(2) N-IikeandM-Iikefunctionofacety1cho1ine(3) TheM-Iikefunction(ocu1arfunction)inducedbypi1ocarpine(4) Anti-Cho1inesterasedrugsAnticho1inergicagentsaimedonM-Cho1inergicreceptor1. Purpose:Graspthecharacteristic

9、s,actionandadversereactionofatropine,anisodamine,hyoscine.2. Content：(1) Atropine,scompetitiveb1ockingfunctiononM-Cho1inergicreceptor(2) Anisodamine,hyoscine,sfunctioncharacteristicsAnticho1inergicagentsaimedonN-Cho1inergicreceptor1. Purpose:Understandthegang1ion(NIandN2receptor)b1ockers,pharmaco1og

10、ica1functionandc1inica1app1ication.Graspthetwomajorkindsofanticho1inergicagentsaimedonN2-Cho1inergicreceptor(ske1eta1musc1ere1axant).2. Content：(I)Gang1ionb1ockersse1ectiveb1ocktheN-receptor.(2)Ske1eta1musc1ere1axantseffectonN2-receptor,(3)Ce1ocaine,sactioncharacteristicsOrganophosphatepoisoningandc

11、ho1inesterasedrugs1. Purpose:Understandtheprincip1e,symptom,preventionandcureoforganophosphatepoisoning;Graspthemechanismofactionandc1inica1app1icationofa1exipharmic2. Content：(1) Themechanismoftheinhibitionofcho1inesteraseinducedbyorganophosphate;(2) Cho1inesterasedrugs:themechanismChapter12adrener

12、gicagonistsandantagonistsAdrenomimetic1. Purpose:Grasptheconceptionandc1assificationoftheadrenergicreceptoragonists.Understandthemechanismandpharmaco1ogica1functionofdrugactivereceptor,1receptorand2receptor.Graspadrena1in,noradrena1inandisoprena1in,sfunction,app1ication,adversereactionsandcontraindi

13、cation.Understandtheactioncharacteristicsandapp1icationofdopamine,ephedrine,A1amin,betweenhydroxy1amineanddobutamine.2. Content：(1) Noradrena1in:themajortargetsofnoradrena1inareand1receptors.Itseffectoncardiovascu1arsystemandc1inica1app1ication,adversereactionandpreventionandcure.(2) Adrena1in:Activ

14、eandreceptors.Itspharmaco1ogica1function,c1inica1app1ication,sideeffectsandcontraindication.(3) Isoprena1in:Active1and2receptors(4) Fami1iarwithInter-hydroxy1amine,dopamine,ephedrine,pheno1D-dopa,sfunctioncharacteristicsandapp1ication.Adrenoreceptorantagonist1. Purpose:Understandtheb1ockingfunctiono

15、nandreceptor,andthec1assification,characteristicsandPhannaco1ogica1actionofandreceptorantagonist.2. Content：Graspthefunctionmechanism,c1inica1meaning,actionanduseofadrenoreceptorantagonistphento1amine,pheno1cummingandto1azo1ine.Chapter18centra1nervoussystempharmaco1ogy-ana1gesics1. Thepurpose:Graspt

16、heactioncharacteristics,c1inica1app1icationandadversereactionofmorphine,pethidine,pentazocineUnderstandtheharmfu1nessofana1gesicdrugsabuse2. Content：(1) 0pium,shistory,c1inica1app1ication,pharmaco1ogica1actionandadversereactions,thec1assificationoftheana1gesics(2) Pharmaco1ogica1actionofmorphine,opiatereceptorc1assif